Apoptosis in Drug Response.

Abstract excerpt

Apoptosis, the cell's intrinsic death program, plays an important role in the regulation of tissue homeostasis. Imbalances between cell death and survival may result in premature death, uncontrolled proliferation or tumor formation. Also, killing of cancer cells by various cytotoxic approaches such as anticancer drugs, gamma-irradiation, suicide genes or immunotherapy, is predominantly mediated through induction o...

Topics

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• Apoptosis
• Cancer-related Molecular Pathways
• Cell death mechanisms and regulation
• Mutation
• Neoplasms
• NF-κB Signaling Pathways
• Oncogenes
• Ubiquitin and proteasome pathways

Identifiers and source

Literature Corpus work

4d13f56b-86cd-5295-9f24-e57e85d68e70

DOI

10.2174/1570160033378358