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Article

Contribution of genetic factors for melanoma susceptibility in sporadic US melanoma patients.

Experimental dermatology - 1 May 2009

Council M Laurin, Gardner Jennifer M, Helms Cynthia, Liu Ying, Cornelius Lynn A, Bowcock Anne M

Abstract excerpt

The risks of developing malignant melanoma (MM) include ultraviolet irradiation and genetic factors. To examine the contribution of rare and common variation within known MM genes in sporadic US MM patients, coding regions of known MM susceptibility genes [cyclin-dependent kinase inhibitor 2A (CDKN2A), cyclin-dependent kinase 4, melanocortin 1 receptor (MC1R) and tyrosinase (TYR)] were resequenced in 109-135 MM...

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Source

Identifiers

PMID: 19320745
DOI: 10.1111/j.1600-0625.2008.00807.x

Genes

TYR

Variants

rs1126809

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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