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Article

Structural basis for the neutralization and genotype specificity of hepatitis E virus.

Proceedings of the National Academy of Sciences of the United States of America - 21 Jun 2011

Tang Xuhua, Yang Chunyan, Gu Ying, Song Cuiling, Zhang Xiao, Wang Yingbin, Zhang Jun, Hew Choy Leong, Li Shaowei, Xia Ningshao, Sivaraman J

Abstract excerpt

Hepatitis E virus (HEV) causes acute hepatitis in humans, predominantly by contamination of food and water, and is characterized by jaundice and flu-like aches and pains. To date, no vaccines are commercially available to prevent the disease caused by HEV. Previously, we showed that a monoclonal antibody, 8C11, specifically recognizes a neutralizing conformational epitope on HEV genotype I. The antibody 8C11...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21642534
DOI: 10.1073/pnas.1101309108
PMCID: PMC3121834

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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