Article
Hepatitis E Virus Mutations: Functional and Clinical Relevance.
EBioMedicine - 1 Sept 2016
van Tong Hoang, Hoan Nghiem Xuan, Wang Bo, Wedemeyer Heiner, Bock C-Thomas, Velavan Thirumalaisamy P
Abstract excerpt
Hepatitis E virus (HEV) infection is a major cause of acute hepatitis and affects more than 20 million individuals, with three million symptomatic cases and 56,000 recognized HEV-related deaths worldwide. HEV is endemic in developing countries and is gaining importance in developed countries, due to increased number of autochthone cases. Although HEV replication is controlled by the host immune system, viral...
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