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Article

Allele-specific, age-dependent and BMI-associated DNA methylation of human MCHR1.

PloS one - 1 Jan 2011

Stepanow Stefanie, Reichwald Kathrin, Huse Klaus, Gausmann Ulrike, Nebel Almut, Rosenstiel Philip, Wabitsch Martin, Fischer-Posovszky Pamela, Platzer Matthias

Abstract excerpt

BACKGROUND: Melanin-concentrating hormone receptor 1 (MCHR1) plays a significant role in regulation of energy balance, food intake, physical activity and body weight in humans and rodents. Several association studies for human obesity showed contrary results concerning the SNPs rs133072 (G/A) and rs133073 (T/C), which localize to the first exon of MCHR1. The variations constitute two main haplotypes (GT, AC)....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21637341
DOI: 10.1371/journal.pone.0017711
PMCID: PMC3102661

Genes

MCHR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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