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HIF3A DNA Methylation Is Associated with Childhood Obesity and ALT

30 Dec 2015

Abstract excerpt

Gene polymorphisms associated so far with body mass index (BMI) can explain only 1.18-1.45% of observed variation in BMI. Recent studies suggest that epigenetic modifications, especially DNA methylation, could contribute to explain part of the missing heritability, and two epigenetic genome-wide analysis studies (EWAS) have reported that Hypoxia Inducible Factor 3 Alpha Subunit (HIF3A) methylation was associated...

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PMID: 26717317
DOI: 10.1371/journal.pone.0145944

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