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Article

Molecular Pathology of Colorectal Cancer

9 Sept 2019

Abstract excerpt

Colorectal cancer (CRC) is the third most commonly diagnosed cancer. This review gives an overview of the current knowledge of molecular mechanisms of colorectal carcinogenesis and the role of molecular testing in the management of CRC. The majority of CRCs arise from precursor lesions such as adenoma, transforming to adenocarcinoma. Three molecular carcinogenesis pathways have been identified; (1) chromosomal...

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PMID: 31503031
DOI: 10.1097/pap.0000000000000247

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