Article
Detection of viral DNA sequences in sporadic colorectal cancers in relation to CpG island methylation and methylator phenotype.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2011
Karpinski Pawel, Myszka Aleksander, Ramsey David, Kielan Wojciech, Sasiadek Maria Malgorzata
Abstract excerpt
There is evidence that insertion of viral DNA into a mammalian genome can lead to alterations of methylation patterns. The aim of the present study was to examine the presence of DNA sequences of five human DNA viruses (assessed by PCR): JC polyoma virus (JCV), human adenovirus (AdV), Epstein-Barr virus (EBV), Kaposi sarcoma-associated herpesvirus (KSHV/HHV8) and human papillomavirus (HPV) in a cohort of 186...
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