Article
Genetic, epigenetic, and clinicopathologic features of gastric carcinomas with the CpG island methylator phenotype and an association with Epstein-Barr virus.
Cancer - 1 Apr 2006
Kusano Masanobu, Toyota Minoru, Suzuki Hiromu, Akino Kimishige, Aoki Fumio, Fujita Masahiro, Hosokawa Masao, Shinomura Yasuhisa, Imai Kohzoh, Tokino Takashi
Abstract excerpt
BACKGROUND: The CpG island methylator phenotype (CIMP), which is characterized by simultaneous methylation of the CpG islands of multiple genes, has been recognized as one of the important mechanisms in gastrointestinal carcinogenesis. METHODS: Methylation of the 5 methylated-in-tumors (MINT) loc...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
