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Article

Association of JC virus T-antigen expression with the methylator phenotype in sporadic colorectal cancers.

Gastroenterology - 1 Jun 2006

Goel Ajay, Li Mei-Shu, Nagasaka Takeshi, Shin Sung Kwan, Fuerst Florentine, Ricciardiello Luigi, Wasserman Linda, Boland C Richard

Abstract excerpt

BACKGROUND & AIMS: JC virus (JCV) is a polyomavirus that ubiquitously infects humans and has been implicated in various human cancers. JCV encodes a "transforming" gene, T-antigen (T-Ag), which is believed to mediate the oncogenic potential of the virus. We have previously shown that JCV DNA sequences are usually present in human colorectal cancers (CRCs), and we have provided in vitro evidence that JCV can...

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Identifiers

PMID: 16762618
DOI: 10.1053/j.gastro.2006.02.061

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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