Article
The basis of differential responses to folic acid supplementation.
Journal of nutrigenetics and nutrigenomics - 1 Jan 2011
Cotlarciuc Ioana, Andrew Toby, Dew Tracy, Clement Gail, Gill Raj, Surdulescu Gabriela, Sherwood Roy, Ahmadi Kourosh R
Abstract excerpt
BACKGROUND/AIMS: Elevated levels of total homocysteine (tHcy) are associated with an increased risk of many common diseases. Supplementation with folic acid has been shown to significantly reduce tHcy levels. We used the classical twin model to partition the variability in changes in plasma tHcy levels through folic acid supplementation into genetic, environmental, and confounding epidemiological factors....
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