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Article

Polygenic association with total homocysteine in the post-folic acid fortification era: the CARDIA study.

Molecular genetics and metabolism - 1 Jan 2000

Tsai Michael Y, Loria Catherine M, Cao Jing, Kim Yongin, Siscovick David S, Schreiner Pamela J, Hanson Naomi Q

Abstract excerpt

Elevated plasma concentration of total homocysteine (tHcy) has been linked with many diseases. tHcy is associated with a variety of factors, including polymorphisms in genes involved in homocysteine metabolism. It is not clear whether US-mandated fortification of grain products with folic acid has affected the association of genetic variants with tHcy levels. We determined tHcy concentrations in sera from 997...

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Source

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Identifiers

PMID: 19577940
DOI: 10.1016/j.ymgme.2009.05.012
PMCID: PMC3578421

Genes

CBS
MTHFR
MTRR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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