Mutational analysis of beta-adrenergic receptor glycosylation.

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Article

Mutational analysis of beta-adrenergic receptor glycosylation.

The Journal of biological chemistry - 25 Jun 1990

Rands E, Candelore M R, Cheung A H, Hill W S, Strader C D, Dixon R A

Abstract excerpt

The beta-adrenergic receptor (beta AR) contains significant amounts of N-linked carbohydrate. Deletion mutants spanning the four consensus glycosylation sites on the receptor and single amino acid substitutions within the two amino-terminal consensus glycosylation sites reveal that both the amino-terminal sites are utilized. None of the glycosylation-defective beta AR mutants exhibited altered ligand binding in...

Topics

Adenylyl Cyclases
Animals
Base Sequence
Cell Line
Chromosome Deletion
Cloning, Molecular
Cricetinae
DNA
Glucosamine
Glycosylation
Guanylyl Imidodiphosphate
Isoproterenol

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Oligonucleotide Probes

Receptors, Adrenergic, beta

Transfection

Tunicamycin

Source

Open in PubMed

Identifiers

PMID: 2162359

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2162359-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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