Article
Cutting edge: an NK cell-independent role for Slamf4 in controlling humoral autoimmunity.
Journal of immunology (Baltimore, Md. : 1950) - 1 Jul 2011
Brown Daniel R, Calpe Silvia, Keszei Marton, Wang Ninghai, McArdel Shannon, Terhorst Cox, Sharpe Arlene H
Abstract excerpt
Several genes within a syntenic region of human and mouse chromosome 1 are associated with predisposition to systemic lupus erythematosus. Analyses of lupus-prone congenic mice have pointed to an important role for the signaling lymphocyte activation molecule family (slamf)6 surface receptor in lupus pathogenesis. In this article, we demonstrate that a second member of the Slamf gene family, Slamf4 (Cd244),...
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