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Article

Mr 92,000 gelatinase release correlates with the metastatic phenotype in transformed rat embryo cells.

Cancer research - 1 Jul 1990

Bernhard E J, Muschel R J, Hughes E N

Abstract excerpt

In a previous study we described a correlation between the metastatic potential of transformed rat embryo cells (REC) and their release of type IV collagenolytic activity (S. Garbisa et al., Cancer Res., 47: 1523-1528, 1987). In the present study, we have identified a Mr 92,000 gelatinase released exclusively by metastatic cell lines in vitro; seven of eight highly metastatic REC lines transformed by H-ras or...

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PMID: 2162246

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