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Article

Mr 92,000 gelatinase release correlates with the metastatic phenotype in transformed rat embryo cells.

Cancer research - 1 Jul 1990

Bernhard E J, Muschel R J, Hughes E N

Abstract excerpt

In a previous study we described a correlation between the metastatic potential of transformed rat embryo cells (REC) and their release of type IV collagenolytic activity (S. Garbisa et al., Cancer Res., 47: 1523-1528, 1987). In the present study, we have identified a Mr 92,000 gelatinase released exclusively by metastatic cell lines in vitro; seven of eight highly metastatic REC lines transformed by H-ras or...

Topics

Animals
Carcinogens
Cells, Cultured
Electrophoresis, Polyacrylamide Gel
Female
Gelatinases
Hydrogen-Ion Concentration
Mice
Mice, Inbred Strains
Molecular Weight
Neoplasm Metastasis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pepsin A

Phenotype

Rats

Time Factors

Transfection

Source

Identifiers

PMID: 2162246

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2162246-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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