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Article

The effect of E1A transfection on MMP-9 expression and metastatic potential.

International journal of cancer - 3 Mar 1995

Bernhard E J, Hagner B, Wong C, Lubenski I, Muschel R J

Abstract excerpt

The expression of MMP-9 in rat embryo fibroblasts (REF) transformed with Ha-ras or with Ha-ras and v-myc is associated with metastatic behavior. In contrast, REF transformed with Ha-ras and the adenovirus E1A genes (E1A) are tumorigenic, do not release MMP-9 and are rarely metastatic. In this report, we establish that E1A expression results in decreased levels of MMP-9 mRNA in an Ha-ras and v-myc transformed cell...

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Source

Identifiers

PMID: 7860147
DOI: 10.1002/ijc.2910600525

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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