Frog PNKT-4B cells express specific extracellular matrix-degrading enzymes and cytokines correlated with an invasive phenotype.

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Article

Frog PNKT-4B cells express specific extracellular matrix-degrading enzymes and cytokines correlated with an invasive phenotype.

The Journal of experimental zoology - 1 Jul 1997

Strissel K J, Tessier M J, Shams N B, Grabbe S, Gross J, Fini M E

Abstract excerpt

A temperature-dependent metastatic phenotype reported for a frog cell line, PNKT-4B, provided a means for studying potential mediators of cell-matrix interaction involved in metastatic invasion. Zymography revealed that these cells secreted enzyme species with properties and characteristics of ma...

Topics

Animals
Anura
Cell Count
Collagenases
Culture Media, Conditioned
Cytokines
DNA
Extracellular Matrix
Fibroblasts
Metalloendopeptidases
Mice
Neoplasm Invasiveness
Phenotype
Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 9206030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9206030-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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