The -930A>G polymorphism of the CYBA gene is associated with premature coronary artery disease. A case-control study and gene-risk factors interactions.

doi:10.1007/s11033-014-3191-9

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

The -930A>G polymorphism of the CYBA gene is associated with premature coronary artery disease. A case-control study and gene-risk factors interactions.

Molecular biology reports - 1 May 2014

Niemiec Pawel, Nowak Tomasz, Iwanicki Tomasz, Krauze Jolanta, Gorczynska-Kosiorz Sylwia, Grzeszczak Wladyslaw, Ochalska-Tyka Anna, Zak Iwona

Abstract excerpt

Reactive oxygen species (ROS) are involved in the pathogenesis of atherosclerosis and coronary artery disease (CAD). NADPH oxidases are the main source of ROS in the vasculature. p22phox is a critical component of vascular NADPH oxidases and is encoded by the CYBA (cytochrome b245 alpha) gene. The -930A>G CYBA polymorphism (rs9932581:A>G) modulates the activity of the CYBA promoter, and influences CYBA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Coronary Artery Disease

Share to Gene Frequency

Share to NADPH Oxidases

Share to Odds Ratio

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 24477591
DOI: 10.1007/s11033-014-3191-9
PMCID: PMC4013450

Genes

CAD
CYBA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The -930A>G polymorphism of the CYBA gene is associated with premature coronary artery disease. A case-control study and gene-risk factors interactions.PMID 24477591Read ↗

G allele of the -930A>G polymorphism of the CYBA gene is associated with insulin resistance in obese subjects.Semantic proximity Read ↗

CYBA gene variants as biomarkers for coronary artery disease.Semantic proximity Read ↗

The effect of p22-PHOX (CYBA) polymorphisms on premature coronary artery disease (≤ 40 years of age).Semantic proximity Read ↗

The CYBA gene A640G polymorphism influences predispositions to coronary artery disease through interactions with cigarette smoking and hypercholesterolemia.Semantic proximity Read ↗

Insight into the role of CYBA A640G and C242T gene variants and coronary heart disease risk. A case-control study.Semantic proximity Read ↗

Relationship of the p22phox (CYBA) gene polymorphism C242T with risk of coronary artery disease: a meta-analysis.Semantic proximity Read ↗

The A640G CYBA polymorphism associates with subclinical atherosclerosis in diabetes.Semantic proximity Read ↗

C242T polymorphism in CYBA gene (p22phox) and risk of coronary artery disease in a population of Caucasian Italians.Semantic proximity Read ↗

The 242T variant of the CYBA gene polymorphism increases the risk of coronary artery disease associated with cigarette smoking and hypercholesterolemia.Semantic proximity Read ↗

The A640G polymorphism in the NAD(P)H oxidase p22phox gene (CYBA) is associated with risk reduction of coronary heart disease: a meta-analysis.Semantic proximity Read ↗

Polymorphisms of C242T and A640G in CYBA gene and the risk of coronary artery disease: a meta-analysis.Semantic proximity Read ↗

The C242T CYBA polymorphism of NADPH oxidase is associated with essential hypertension.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.