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Article

Association between single nucleotide polymorphisms in the DNA repair gene LIG3 and acute adverse skin reactions following radiotherapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 May 2011

Murray Robert J S, Tanteles George A, Mills Jamie, Perry Angus, Peat Irene, Osman Ahmed, Chan Steve, Cheung Kwok-Leung, Chakraborti Prabir R, Woodings Pamela L, Barwell Julian G, Symonds R Paul, Talbot Christopher J

Abstract excerpt

Many genes have been associated with radiotherapy toxicity, but most have only been found in a single study. Using our cohort of 480 breast cancer patients, we provide replicated evidence that a polymorphism near the LIG3 gene is associated with acute skin toxicity following radiotherapy.

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Source

Identifiers

PMID: 21620500
DOI: 10.1016/j.radonc.2011.05.007

Genes

LIG3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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