Article
A replicated association between polymorphisms near TNFα and risk for adverse reactions to radiotherapy.
British journal of cancer - 7 Aug 2012
Talbot C J, Tanteles G A, Barnett G C, Burnet N G, Chang-Claude J, Coles C E, Davidson S, Dunning A M, Mills J, Murray R J S, Popanda O, Seibold P, West C M L, Yarnold J R, Symonds R P
Abstract excerpt
BACKGROUND: Response to radiotherapy varies between individuals both in terms of efficacy and adverse reactions. Finding genetic determinants of radiation response would allow the tailoring of the treatment, either by altering the radiation dose or by surgery. Despite a growing number of studies in radiogenomics, there are no well-replicated genetic association results. METHODS: We carried out a candidate gene...
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