Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sex-Biased Expression of Pharmacogenes across Human Tissues

13 Aug 2021

Abstract excerpt

Individual response to drugs is highly variable and largely influenced by genetic variants and gene-expression profiles. In addition, it has been shown that response to drugs is strongly sex-dependent, both in terms of efficacy and toxicity. To expand current knowledge on sex differences in the expression of genes relevant for drug response, we generated a catalogue of differentially expressed human transcripts...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hormonal Regulation and Hypertension
Share to Pharmacogenetics and Drug Metabolism
Share to Receptor Mechanisms and Signaling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34439872
DOI: 10.3390/biom11081206

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sex-Biased Expression of Pharmacogenes across Human TissuesPMID 34439872Read ↗

Sex-biased Expression of Pharmacogenes Across Human TissuesSemantic proximity Read ↗

Sex Differences in the Expression of Drug-Metabolizing and Transporter Genes in Human LiverSemantic proximity Read ↗

Sex-biased gene expression and gene-regulatory networks of sex-biased adverse event drug targets and drug metabolism genesSemantic proximity Read ↗

Pharmacogenomics of sex difference in chemotherapeutic toxicity.Semantic proximity Read ↗

Effects of testosterone on gene expression in males and females across 40 human tissues.Semantic proximity Read ↗

Sex dependent gene activity in the human bodySemantic proximity Read ↗

Transcriptomic variation of pharmacogenes in multiple human tissues and lymphoblastoid cell lines.Semantic proximity Read ↗

A New Liver Expression Quantitative Trait Locus Map From 1,183 Individuals Provides Evidence for Novel Expression Quantitative Trait Loci of Drug Response, Metabolic, and Sex-Biased Phenotypes.Semantic proximity Read ↗

Sex- and age-dependent gene expression in human liver: An implication for drug-metabolizing enzymesSemantic proximity Read ↗

The impact of sex on gene expression across human tissues.Semantic proximity Read ↗

Transcriptional regulation and pharmacogenomics.Semantic proximity Read ↗

En route to precision medicine through the integration of biological sex into pharmacogenomicsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.