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Pharmacogenomics of Drug Metabolizing Enzymes and Transporters: Relevance to Precision Medicine

1 Oct 2016

Abstract excerpt

The interindividual genetic variations in drug metabolizing enzymes and transporters influence the efficacy and toxicity of numerous drugs. As a fundamental element in precision medicine, pharmacogenomics, the study of responses of individuals to medication based on their genomic information, enables the evaluation of some specific genetic variants responsible for an individual's particular drug response. In this...

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PMID: 27729266
DOI: 10.1016/j.gpb.2016.03.008

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