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Article

Pharmacogenomics: the influence of genomic variation on drug response.

Current topics in medicinal chemistry - 1 Jan 2004

Thomas Fabienne J, McLeod Howard L, Watters James W

Abstract excerpt

Unpredictable efficacy and toxicity are major hurdles in the administration of many medications. By identifying inherited DNA polymorphisms that influence drug disposition and effects, pharmacogenomics is an exciting tool for the individualization of drug therapies. Single nucleotide polymorphisms (SNP) in genes encoding drug metabolizing enzymes, drug transporters, and DNA repair genes have recently been shown...

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PMID: 15379653
DOI: 10.2174/1568026043387638

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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