Article
Abelson kinase (Abl) and RhoGEF2 regulate actin organization during cell constriction in Drosophila.
Development (Cambridge, England) - 1 Feb 2007
Fox Donald T, Peifer Mark
Abstract excerpt
Morphogenesis involves the interplay of different cytoskeletal regulators. Investigating how they interact during a given morphogenetic event will help us understand animal development. Studies of ventral furrow formation, a morphogenetic event during Drosophila gastrulation, have identified a signaling pathway involving the G-protein Concertina (Cta) and the Rho activator RhoGEF2. Although these regulators act...
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