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Article

Rap1 and Canoe/afadin are essential for establishment of apical-basal polarity in the Drosophila embryo.

Molecular biology of the cell - 1 Apr 2013

Choi Wangsun, Harris Nathan J, Sumigray Kaelyn D, Peifer Mark

Abstract excerpt

The establishment and maintenance of apical-basal cell polarity is critical for assembling epithelia and maintaining organ architecture. Drosophila embryos provide a superb model. In the current view, apically positioned Bazooka/Par3 is the initial polarity cue as cells form during cellularization. Bazooka then helps to position both adherens junctions and atypical protein kinase C (aPKC). Although a polarized...

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Identifiers

PMID: 23363604
DOI: 10.1091/mbc.E12-10-0736
PMCID: PMC3608504

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Rap1 and Canoe/afadin are essential for establishment of apical-basal polarity in the Drosophila embryo.PMID 23363604Read ↗

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