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Article

Mammalian Llgl2 is necessary for proper branching morphogenesis during placental development.

Molecular and cellular biology - 1 Jul 2011

Sripathy Smitha, Lee Minhui, Vasioukhin Valeri

Abstract excerpt

Cell polarity plays a critical role in the development of all metazoans; however, the mechanisms of cell polarity and the specific role of cell polarity pathways in mammalian organisms are still poorly understood. Lethal giant larvae (Lgl) is an apical-basal polarity gene identified in Drosophila, where it functions as a tumor suppressor controlling self-renewal and differentiation of progenitor cells. There are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21606200
DOI: 10.1128/MCB.05431-11
PMCID: PMC3133403

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