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Article

A <i>Grhl2</i>-dependent gene network controls trophoblast branching morphogenesis

10 Mar 2015

Abstract excerpt

Healthy placental development is essential for reproductive success; failure of the feto-maternal interface results in pre-eclampsia and intrauterine growth retardation. We found that grainyhead-like 2 (GRHL2), a CP2-type transcription factor, is highly expressed in chorionic trophoblast cells, including basal chorionic trophoblast (BCT) cells located at the chorioallantoic interface in murine placentas....

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PMID: 25758223
DOI: 10.1242/dev.113829

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