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Article

Receptor activation and 2 distinct COOH-terminal motifs control G-CSF receptor distribution and internalization kinetics.

Blood - 15 Jan 2004

Aarts Lambertus H J, Roovers Onno, Ward Alister C, Touw Ivo P

Abstract excerpt

We have studied the intracellular distribution and internalization kinetics of the granulocyte colony-stimulating factor receptor (G-CSF-R) in living cells using fusion constructs of wild-type or mutant G-CSF-R and enhanced green fluorescent protein (EGFP). Under steady-state conditions the G-CSF-R localized predominantly to the Golgi apparatus, late endosomes, and lysosomes, with only low expression on the...

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Identifiers

PMID: 14512302
DOI: 10.1182/blood-2003-07-2250

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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