Article
Molecular biology of macrophage colony-stimulating factor.
Immunology series - 1 Jan 1990
Kawasaki E S, Ladner M B
Abstract excerpt
In this chapter we have described one of the more complex hemopoietic factors, M-CSF. The single-copy M-CSF gene is almost 21 kb in length and is arranged into 10 exons and 9 introns. Expression of the gene at the RNA level is heterogeneous, and several species of M-CSF mRNA have been found in human and murine cells and tissues. In human cells the different mRNAs arise from alternative splicing of the nuclear RNA...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- DNA
- Gene Expression
- Humans
- Macrophage Colony-Stimulating Factor
- Mice
- Molecular Sequence Data
- Mutation