Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dissecting the pleiotropic genetic architecture of suicide attempt, suicidal ideation, and thirteen correlated traits.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Jul 2026

Martone Alfonso, Folego-Temoteo Isabella, Fries Gabriel R, Docherty Anna R, Ashley-Koch Allison E, Bandeira Cibele E, Grevet Eugenio H, Bau Claiton H D, Bralten Janita, Fabbri Chiara, Serretti Alessandro, Fanelli Giuseppe, Rovaris Diego L

Abstract excerpt

Suicide attempts (SA) and suicidal ideation (SI) are major public health concerns with incompletely understood underlying genetic and molecular mechanisms. We investigated the shared genetic architecture of SA and SI with 13 genetically correlated psychiatric, behavioural, and somatic phenotypes using summary statistics from 15 genome-wide association studies (N=46,350-975,353). Local Analysis of [co]Variant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Pleiotropy
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Phenotype

Share to Suicidal Ideation

Share to Suicide, Attempted

Source

Identifiers

PMID: 41950637
DOI: 10.1016/j.euroneuro.2026.112821

Genes

SI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dissecting the pleiotropic genetic architecture of suicide attempt, suicidal ideation, and thirteen correlated traits.PMID 41950637Read ↗

In-Depth characterization of the shared genetic architecture of suicide attempts with other major psychiatric disorders.Semantic proximity Read ↗

Genome-wide association study meta-analysis of suicide attempt identifies twelve genome-wide significant loci and implicates genetic risks for specific health factorsSemantic proximity Read ↗

GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors.Semantic proximity Read ↗

Multivariate genome-wide association study of suicidal behaviors in >1.7 million individuals of diverse population descentsSemantic proximity Read ↗

Genetic contributions to suicidal thoughts and behaviors.Semantic proximity Read ↗

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors.Semantic proximity Read ↗

Polygenic risk scores for psychiatric, inflammatory, and cardio-metabolic traits and diseases highlight possible genetic overlaps with suicide attempt and treatment-emergent suicidal ideationSemantic proximity Read ↗

Genetic relationships and biobehavioral pathways between suicidality and comorbid mental disorders: a comprehensive cross-phenotype analysisSemantic proximity Read ↗

Mapping the genetic landscape of suicide risk: Insights from genomic SEM.Semantic proximity Read ↗

Polygenic risk scores for neuropsychiatric, inflammatory, and cardio-metabolic traits highlight possible genetic overlap with suicide attempt and treatment-emergent suicidal ideation.Semantic proximity Read ↗

Functional and molecular characterization of suicidality factors using phenotypic and genome-wide data.Semantic proximity Read ↗

Deciphering the shared genetic architecture between schizophrenia and suicide attempt: a statistical genomic study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.