Family environment interacts with CRHR1 rs17689918 to predict mental health and behavioral outcomes.

doi:10.1016/j.pnpbp.2018.05.004

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Article

Family environment interacts with CRHR1 rs17689918 to predict mental health and behavioral outcomes.

Progress in neuro-psychopharmacology & biological psychiatry - 30 Aug 2018

Roy Arunima, Laas Kariina, Kurrikoff Triin, Reif Andreas, Veidebaum Toomas, Lesch Klaus-Peter, Harro Jaanus

Abstract excerpt

BACKGROUND: Corticotrophin-releasing hormone receptor-1 gene (CRHR1) variants have been implicated in mental health. However, little is known of the effects of CRHR1 on long-term mental health and behavior in presence of environmental stressors. We assess the effects of CRHR1 variant (rs17689918)-by-environment interactions on emotionality and behavioral traits, including anxiety, depression, aggression and...

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Identifiers

PMID: 29772307
DOI: 10.1016/j.pnpbp.2018.05.004

Genes

CRHR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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