Article
Family-based study of HTR2A in suicide attempts: observed gene, gene × environment and parent-of-origin associations.
Molecular psychiatry - 1 Jul 2013
Ben-Efraim Y J, Wasserman D, Wasserman J, Sokolowski M
Abstract excerpt
While suicidal behavior is frequently accompanied by serotonergic system alterations, specific associations with genetic variation in the serotonin 2A receptor (HTR2A) gene have been inconsistent. Using a family-based study design of 660 offspring who have made a suicide attempt (SA) and both parents, we conducted an association and linkage analysis using single-nucleotide polymorphisms (SNPs) with extensive gene...
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