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Article

MMP-3 (5A/6A) polymorphism does not influence human smooth muscle cell invasion.

The Journal of surgical research - 15 Jun 2012

Maqbool Azhar, Keswani Anita, Galloway Stacey, O'Regan David J, Ball Stephen G, Turner Neil A, Porter Karen E

Abstract excerpt

BACKGROUND: Stromelysin (MMP-3) is an important regulator of vascular smooth muscle cell (SMC) invasion, a key contributor to saphenous vein (SV) bypass graft failure. The 5A allele of the common -1612 MMP-3 5A/6A promoter polymorphism reportedly confers increased promoter activity, MMP-3 tissue expression, and susceptibility to a number of vascular pathologies. The aim of this study was to determine whether the...

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Source

Identifiers

PMID: 21601886
DOI: 10.1016/j.jss.2011.03.043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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MMP-3 (5A/6A) polymorphism does not influence human smooth muscle cell invasion.PMID 21601886Read ↗

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