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Article

The 5A/6A polymorphism of the matrix metalloproteinase 3 gene promoter and breast cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 May 2004

Krippl Peter, Langsenlehner Uwe, Renner Wilfried, Yazdani-Biuki Babak, Köppel Herwig, Leithner Andreas, Wascher Thomas C, Paulweber Bernhard, Samonigg Hellmut

Abstract excerpt

PURPOSE: The matrix metalloproteinase 3 (MMP3), also known as stromelysin-I, is a key-player for carcinogenesis and tumor growth. A 5A/6A promoter polymorphism is associated with differences in MMP3 activity and has been linked to cancer susceptibility in some studies. In the present study we evaluated the role of this polymorphism for breast cancer risk. EXPERIMENTAL DESIGN: A case-control study was performed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15161710
DOI: 10.1158/1078-0432.CCR-04-0010

Genes

MMP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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