Article
Stromelysin-1 (MMP-3) gene 5A/6A promoter polymorphism is associated with blood pressure in a community population.
Journal of hypertension - 1 Mar 2005
Beilby John P, Chapman Caroline M L, Palmer Lyle J, McQuillan Brendan M, Thompson Peter L, Hung Joseph
Abstract excerpt
BACKGROUND AND OBJECTIVES: Arterial remodelling contributes to the development of hypertension. Stromelysin-1 (MMP-3), a member of the matrix metalloproteinase family may contribute to this process. Stromelysin-1 gene expression is partly regulated by a common polymorphism in the promoter region of either five or six consecutive adenosine bases (5A/6A). METHODS AND RESULTS: A cross-sectional study of 1111...
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