Article
A dopamine receptor (DRD2) but not dopamine transporter (DAT1) gene polymorphism is associated with neurocognitive development of Mexican preschool children with lead exposure.
The Journal of pediatrics - 1 Oct 2011
Kordas Katarzyna, Ettinger Adrienne S, Bellinger David C, Schnaas Lourdes, Téllez Rojo Martha María, Hernández-Avila Mauricio, Hu Howard, Wright Robert O
Abstract excerpt
OBJECTIVE: To investigate the effects of prenatal and postnatal lead exposure and polymorphisms in dopamine metabolism genes on neurocognitive development of Mexican children at 24 months (n = 220) and 48 months (n = 186) of age. STUDY DESIGN: We genotyped the dopamine transporter gene (DAT1; SLC6A3) variable nucleotide tandem repeat and the dopamine receptor D2 (DRD2) Taq1A single nucleotide polymorphism....
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