Article
Hemoglobin, lead exposure, and intelligence quotient: effect modification by the DRD2 Taq IA polymorphism.
Environmental health perspectives - 1 Jan 2011
Roy Ananya, Hu Howard, Bellinger David C, Mukherjee Bhramar, Modali Rama, Nasaruddin Khaja, Schwartz Joel, Wright Robert O, Ettinger Adrienne S, Palaniapan Kavitha, Balakrishnan Kalpana
Abstract excerpt
BACKGROUND: Anemia and lead exposure remain significant public health issues in many parts of the world, often occurring together. Animal studies suggest that the dopamine D2 receptor (DRD2) mediates the effects of both lead and iron on cognition and behavior. OBJECTIVE: We tested the hypothesis that the DRD2 Taq IA polymorphism modifies the effects of lead and hemoglobin on intelligence quotient (IQ) among...
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