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Genetic Susceptibility to Neurotoxicity Related to Prenatal Inorganic Arsenic Exposure in Young Spanish Children.

Environmental science & technology - 17 Oct 2023

Soler-Blasco Raquel, Llop Sabrina, Riutort-Mayol Gabriel, Lozano Manuel, Vallejo-Ortega Jorge, Murcia Mario, Ballester Ferran, Irizar Amaia, Andiarena Ainara, Fernandez-Jimenez Nora, Braeuer Simone, Harari Florencia

Abstract excerpt

We explored the influence of child and maternal single nucleotide polymorphisms (SNPs) in genes related to neurological function and arsenic metabolism (i.e., ABCA1, ABCB1, PON1, CYP3A, BDNF, GSTP1, MT2A, and APOE as well as AS3MT) on the association between prenatal arsenic (As) exposure and methylation efficiency and neuropsychological development in 4-5-year-old children. Participants were 549 mother-child...

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PMID: 37787746
DOI: 10.1021/acs.est.3c03336

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