Article
Assessment of association between the dopamine D2 receptor (DRD2) polymorphism and neurodevelopment of children exposed to lead.
Environmental science and pollution research international - 1 Feb 2015
Liu Lian, Xu Xijin, Yekeen Taofeek Akangbe, Lin Kun, Li Weiqiu, Huo Xia
Abstract excerpt
The mechanism of lead (Pb) neurotoxicity has not been illustrated over the years. People pay more attention to dopaminergic neurotransmission, specifically dopamine receptor-2 (DRD2) Taq IA polymorphism, but no consensus has been reached. A total of 258 three-year-old children in Guiyu (exposed group) and Nanao (reference group), China were examined and their concentrations of blood lead (BPb) were determined....
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