Article
Polymorphisms in ATP-binding cassette transporters associated with maternal methylmercury disposition and infant neurodevelopment in mother-infant pairs in the Seychelles Child Development Study.
Environment international - 1 Sept 2016
Engström Karin, Love Tanzy M, Watson Gene E, Zareba Grazyna, Yeates Alison, Wahlberg Karin, Alhamdow Ayman, Thurston Sally W, Mulhern Maria, McSorley Emeir M, Strain J J, Davidson Philip W, Shamlaye Conrad F, Myers G J, Rand Matthew D, van Wijngaarden Edwin, Broberg Karin
Abstract excerpt
BACKGROUND: ATP-binding cassette (ABC) transporters have been associated with methylmercury (MeHg) toxicity in experimental animal models. AIMS: To evaluate the association of single nucleotide polymorphisms (SNPs) in maternal ABC transporter genes with 1) maternal hair MeHg concentrations during pregnancy and 2) child neurodevelopmental outcomes. MATERIALS AND METHODS: Nutrition Cohort 2 (NC2) is an...
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