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Article

High level expression of wild type and variant mouse glucocorticoid receptors in Chinese hamster ovary cells.

Molecular endocrinology (Baltimore, Md.) - 1 Jan 1990

Hirst M A, Northrop J P, Danielsen M, Ringold G M

Abstract excerpt

We have isolated Chinese hamster ovary (CHO) cell lines expressing elevated levels of wild-type (W) and mutant forms of the glucocorticoid receptor (GR) using the technique of coamplification with a selectable dihydrofolate reductase (dhfr) cDNA. A prominent doublet at 90/92 kilodaltons was observed by Western blotting or labeling with [3H]-dexamethasone mesylate in extracts from cells transfected with W, the...

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Identifiers

PMID: 2157974
DOI: 10.1210/mend-4-1-162

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CAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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