Glucocorticoid-dependent maturation of mouse mammary tumor virus glycoproteins in mouse lymphoma cells: isolation of variants with constitutive viral protein maturation and normal glucocorticoid receptor function.

doi:10.1210/mend-4-2-341

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Article

Glucocorticoid-dependent maturation of mouse mammary tumor virus glycoproteins in mouse lymphoma cells: isolation of variants with constitutive viral protein maturation and normal glucocorticoid receptor function.

Molecular endocrinology (Baltimore, Md.) - 1 Feb 1990

Byravan S, Stallcup M R

Abstract excerpt

The posttranslational maturation and cell surface localization of mouse mammary tumor virus (MMTV) envelope glycoproteins is regulated by glucocorticoid hormone in mouse T-lymphoma cell line W7MG1. Only when the cells are cultured with glucocorticoid is the MMTV envelope precursor, Pr74, converted efficiently to the two mature proteolytic products, gp52 and gp33. By immunological selection we have isolated...

Topics

Animals
Antigens, Viral, Tumor
Cell Line
Cell Membrane
Electrophoresis, Gel, Two-Dimensional
Genetic Variation
Glucocorticoids
Glycoproteins
Hybrid Cells
Lymphoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mammary Neoplasms, Experimental

Mice

Phenotype

Receptors, Glucocorticoid

T-Lymphocytes

Viral Proteins

Source

Open in PubMed

Identifiers

PMID: 2330009
DOI: 10.1210/mend-4-2-341

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2330009-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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