Kappa light chain gene rearrangement in T-cell acute lymphoblastic leukemia.

doi:10.1093/ajcp/93.4.563

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Article

Kappa light chain gene rearrangement in T-cell acute lymphoblastic leukemia.

American journal of clinical pathology - 1 Apr 1990

Hanson C A, Thamilarasan M, Ross C W, Stoolman L M, Schnitzer B

Abstract excerpt

Immunoglobulin and T-cell receptor gene rearrangement assays are sensitive methods of detecting clonality in lymphoproliferative disorders. The lack of lineage specificity of immunoglobulin heavy chain and T-cell receptor beta and gamma gene probes in acute leukemia is well established. However,...

Topics

Aged
Bone Marrow
Gene Rearrangement, T-Lymphocyte
Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
Genes, Immunoglobulin
Humans
Immunoglobulin Light Chains
Leukemia-Lymphoma, Adult T-Cell
Male
Phenotype

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