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Article

Gene Rearrangements in the Diagnosis of Lymphoma/Leukemia: Guidelines for Use Based on a Multiinstitutional Study

1 Mar 1991

Abstract excerpt

The demonstration of immunoglobulin or T-cell receptor gene rearrangements in human lymphoproliferative processes with the use of DNA hybridization has gained great popularity as a sensitive laboratory adjunct to diagnostic hematopathology. The fact that nearly all B- or T-cell malignant lymphomas and leukemias have one or more rearranged antigen receptor genes provides a biologic basis for a diagnostic test. To...

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PMID: 1996544
DOI: 10.1093/ajcp/95.3.347

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Gene Rearrangements in the Diagnosis of Lymphoma/Leukemia: Guidelines for Use Based on a Multiinstitutional StudyPMID 1996544Read ↗

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