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Analysis of rearranged T-cell receptor beta-chain genes by polymerase chain reaction (PCR) DNA sequencing and automated high resolution PCR fragment analysis

15 Nov 1995

Abstract excerpt

Polymerase chain reaction (PCR)-directed amplification and sequencing of rearranged immune genes for identification of clone-specific markers are increasingly being used in acute lymphoblastic leukemia (ALL) and non-Hodgkin's lymphoma (NHL) patients instead of the time consuming and labor intensive Southern analysis. In previous reports, no single common V beta and J beta sequence had been identified that allowed...

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PMID: 7579363
DOI: 10.1182/blood.v86.10.3930.bloodjournal86103930

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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