Article
Lineage promiscuity in leukemia studies of T-cell receptor and immunoglobulin genes.
Leukemia research - 1 May 1993
Bernard D, Bignon Y J, Lavenue F, Pauchard J, Demeocq F, Travade P, Philippe P, Legros M, Cure H, Chassagne J
Abstract excerpt
Using appropriate DNA probes, the configurations of the T-cell receptor beta-chain genes and immunoglobulin heavy-chain genes were studied in patients diagnosed as having the following malignancies: 7 chronic myeloid leukemia, 13 acute myeloblastic leukemia, 9 acute lymphocytic leukemia and 20 chronic lymphocytic leukemia. Rearrangements not corresponding to the immunotype were unexpectedly found in lineage...
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