Kappa immunoglobulin light chain gene rearrangement in a T-lineage chronic lymphocytic leukemia.

Abstract excerpt

Until recently, only B-lineage lymphoid cells were observed to rearrange kappa immunoglobulin light chain genes. The authors examine peripheral blood mononuclear cells from a patient with chronic lymphocytic leukemia. More than 90% of these cells bound T-lymphocyte specific antibodies, failed to bind B-lymphocyte specific antibodies, had rearranged T-cell receptor beta-chain genes and had retained immunoglobulin...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Antigens, CD
• Share to DNA, Neoplasm
• Share to Gene Rearrangement, T-Lymphocyte