Article
Effect of age and gender on the progression of adult vascular dysfunction in a mouse model of fetal programming lacking endothelial nitric oxide synthase.
American journal of physiology. Heart and circulatory physiology - 1 Aug 2011
Chiossi Giuseppe, Costantine Maged M, Tamayo Esther, Orise Phyllis, Hankins Gary D V, Saade George R, Longo Monica
Abstract excerpt
The objective of this study was to investigate vascular function at different ages in a transgenic murine model of fetal vascular programming using a model of uteroplacental insufficiency induced by lack of endothelial nitric oxide synthase. Homozygous NOS3 knockout (KO) and wild-type (WT) mice w...
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