Article
Perinatal development of endothelial nitric oxide synthase-deficient mice.
Biology of reproduction - 1 Feb 2001
Hefler L A, Reyes C A, O'Brien W E, Gregg A R
Abstract excerpt
The purpose of this study was to evaluate the influence of endothelial nitric oxide synthase (eNOS) deficiency on fetal growth, perinatal survival, and limb development in a mouse model with a targeted mutagenesis of the Nos3 gene. Wild-type (Nos3+/+) and eNOS-deficient fetuses (Nos3-/-) were evaluated on Gestational Day (E)15 and E17, and newborn pups were observed on Day 1 of life (D1). The average term...
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