Article
Epigenetics and transcriptional control in African trypanosomes.
Essays in biochemistry - 20 Sept 2010
Rudenko Gloria
Abstract excerpt
The African trypanosome Trypanosoma brucei is a unicellular parasite which causes African sleeping sickness. Transcription in African trypanosomes displays some unusual features, as most of the trypanosome genome is transcribed as extensive polycistronic RNA Pol II (polymerase II) transcription units that are not transcriptionally regulated. In addition, RNA Pol I is used for transcription of a small subset of...
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